Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance
, treatment with pioglitazone in patients with impaired glucose tolerance reduced the risk of diabetes, although pioglitazone was associated with significant weight gain and edema. Use of pioglitazone improved
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Olmesartan for the Delay or Prevention of Microalbuminuria in Type 2 Diabetes
Microalbuminuria is predictive of diabetic nephropathy and premature cardiovascular disease; therefore, European and American guidelines recommend that patients with diabetes be tested for microalbuminuria.
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Apixaban in Patients with Atrial Fibrillation
Vitamin K antagonists have been shown to prevent stroke in patients with atrial fibrillation. However, many patients are not suitable candidates for, or are unwilling to receive, vitamin K antagonist therapy, and these patients have a high risk of stroke.
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Anticoagulant Options — Why the FDA Approved a Higher but Not a Lower Dose of Dabigatran
the Food and Drug Administration (FDA) approved dabigatran for the reduction of the risk of stroke and systemic embolism in patients with
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Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data
Combinations of aspirin, clopidogrel, and vitamin K antagonists are widely used in patients after myocardial infarction. However, data for the safety of combinations are sparse.
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